Solid Clumps of Bio-Material can be found rather often. However, only a few can upgrade alien weapons. Usually the Bio-Materials for upgrading alien weapons can be found on the city raid 'boss' and the 'boss' on the alien ship.
You can pre-check the kind of Bio-Material you have looted by asking your prefered bot (eg. your org bot) with the 'inspect' or 'bio' command, or by placing it in the tradeskill interface along with a Kyr'Ozch Structural Analyzer. For Bio-Material used for city buildings please look at our City Building Guide.
To convert your Bio-Material clump from its unprocessed state, you now need to tradeskill. As an example:
To combine the bio-material clump with an untyped weapon, the weapon must support that type. Also, the clump needs to be at least 90% of the QL of the weapon. Once a weapon has been typed, you cannot add another type to the weapon or clear the type.